Ellen J. MacKenzie, PhD

Fred and Julie Soper Professor and Chair, Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health

Dr. Ellen MacKenzie is the Fred and Julie Soper Professor and Chair of the Department of Health Policy and Management of the Johns Hopkins Bloomberg School of Public Health.  She is a graduate of the Bloomberg School where she earned her doctoral degree in biostatistics. She holds joint appointments in the Departments of Emergency Medicine and Physical Medicine and Rehabilitation at the School of Medicine.  In addition to her faculty appointments, Dr. MacKenzie served as Senior Associate Dean at the School from 1996 to 2000 and Director of the Center for Injury Research and Policy from 1995-2005.

Dr. MacKenzie’s research has focused on the impact of health services and policies on the physical and mental health consequences of traumatic injury. She has contributed to the development and evaluation of tools for measuring the severity and outcome of injury. Her research has advanced the knowledge of the economic and social impact of injuries and our understanding of how personal and environmental factors influence recovery and return to work. Dr. MacKenzie's recent work includes: a national evaluation of the cost and effectiveness of trauma systems; an evaluation of the long-term outcomes of amputation versus limb salvage; the development and evaluation of in-person and on-line self-management programs following trauma and limb loss (http://nextstepsonline.org/); and collaboration with the American Trauma Society in the development and evaluation of the Trauma Survivors Network (TSN) (http://www.traumasurvivorsnetwork.org/)– an integrated approach to provide efficient access to information, peer support and self-management training  for trauma patients and their families seeking to rebuild their lives following serious injury.

Most recently, she has joined colleagues from around the country to establish the Major Extremity Trauma Research Consortium (METRC) (www.metrc.org). With core funding from the U.S. Department of Defense, the goal of METRC is to produce the evidence needed to establish treatment guidelines for the optimal care of the wounded warrior and improve the clinical, functional and quality of life outcomes of both service members and civilians who sustain high energy orthopaedic trauma. Anchored by a Coordinating Center at the Bloomberg School of Public Health, METRC is comprised of 22 Level I civilian trauma centers and 4 Military Treatment Facilities, with the ability to expand recruitment to more than 30 satellite centers around the country.

METRC is currently funded by DoD and NIH to conduct 14 prospective studies.  Examples include:

  • RCTs to evaluate approaches to the prevention of deep surgical site infections (e.g. use of external ring fixation vs. intramedullary  nailing; use of supplemental perioperative oxygen; use of local Vancomycin powder);
  • RCTs to evaluate the effectiveness of adjunctive analgesic therapy during the pre and peri-operative period in improving pain related outcomes without related side effects;
  • Prospective study to develop a model that predicts the likelihood of Acute Compartment Syndrome based on continuous monitoring of intramuscular pressures and muscle oxygenation;
  • Clinical trial evaluating the effectiveness of a new dynamic exoskeletal orthosis developed by the military for improving function and quality of life for patients with severe foot and ankle injuries;
  • Clinical trial to evaluate the effectiveness of a Trauma Collaborative Care intervention that incorporates access to peer support and self-management through the Trauma Survivors Network (TSN); training of providers to screen for and promote use of clinical guidelines for management of psychological comorbidities; and use of a Recovery Coach to motivate use of services and promote communication between providers and patients;
  • A study to evaluate use of the NIH PROMIS technology and computer adaptive testing in measuring outcomes following orthopaedic trauma.

Her awards include the A.J. Mirkin Service Award from the Association for the Advancement of Automotive Medicine, the Ann Doner Vaughan Kappa Delta Award from the American Academy of Orthopaedic Surgeons, the Distinguished Career Award from the American Public Health Association (Injury Control and Emergency Health Services Section) and the American Trauma Society's Distinguished Achievement Award. She is also an honorary fellow of the American Association for the Surgery of Trauma and in 2012 was named by CDC as one of 20 leaders and visionaries who have had a transformative effect on the field of violence and injury prevention over the past 20 years.

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November 2017

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